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A Multicentered, Single-group Phase 2, Exploratory, Open-label Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in the Treatment of Adult Participants With Immunoglobulin A Nephropathy (IgAN)

Trial Profile

A Multicentered, Single-group Phase 2, Exploratory, Open-label Study to Investigate Safety and Effect of Sparsentan in Combination With SGLT2 Inhibition in the Treatment of Adult Participants With Immunoglobulin A Nephropathy (IgAN)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Nov 2025

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At a glance

  • Drugs Sparsentan (Primary) ; Sodium-glucose transporter 2 inhibitors
  • Indications IgA nephropathy
  • Focus Therapeutic Use
  • Acronyms SPARTACUS
  • Sponsors Travere Therapeutics

Most Recent Events

  • 03 Jun 2025 According to Travere Therapeutics Inc media release, abstracts from the trial will be presented at the upcoming European Renal Association (ERA) Congress in Vienna, Austria, June 4-7.
  • 07 Nov 2024 Status changed from active, no longer recruiting to completed.
  • 26 Oct 2024 According to a Travere Therapeutics media release, data from this study were presented at the American Society of Nephrology (ASN).

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