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proSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors

Trial Profile

proSpecTive sAmpling in dRiver muTation Pulmonary Oncology Patients on Tyrosine Kinase Inhibitors

Status: Recruiting
Phase of Trial: Phase IV

Latest Information Update: 12 Dec 2023

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At a glance

  • Drugs Sotorasib (Primary)
  • Indications Liver metastases; Non-small cell lung cancer
  • Focus Pharmacokinetics
  • Acronyms START-TKI

Most Recent Events

  • 24 Oct 2023 Results (At data cut off: 28 April 2023, n=90) assessing potential association between the time interval between prior IO and sotorasib and the incidence of severe hepatotoxicity, presented at the 48th European Society for Medical Oncology Congress.
  • 17 May 2023 New trial record
  • 19 Apr 2023 Results(n=35) assessing Clinical utility of circulating tumor DNA in patients with advanced KRAS G12C-mutated NSCLC treated with sotorasib presented at the 114th Annual Meeting of the American Association for Cancer Research

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