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Phase Ia first in human randomized, double-blind, placebo-controlled trial assessed the safety, tolerability and pharmacokinetics (PK) of single and multiple ascending doses of THN391 in healthy volunteers

Trial Profile

Phase Ia first in human randomized, double-blind, placebo-controlled trial assessed the safety, tolerability and pharmacokinetics (PK) of single and multiple ascending doses of THN391 in healthy volunteers

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 06 May 2025

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At a glance

  • Drugs THN 391 (Primary)
  • Indications Alzheimer's disease; Hyperlipidaemia; Hypertension; Type 2 diabetes mellitus
  • Focus Adverse reactions; First in man
  • Sponsors Therini Bio

Most Recent Events

  • 29 Apr 2025 Results presented in the Therini Bio media release.
  • 29 Apr 2025 According to Therini Bio media release, the company announced the data from this study will be presented at the Alzheimer's Association International Conference 2025 (AAIC 25) in Toronto, Canada, on Wednesday, July 30, 2025.
  • 24 Oct 2023 According to Therini Bio media release, the interim data will be detailed in a poster presentation at the 16th Clinical Trials on Alzheimer's Disease (CTAD) conference taking place from October 25-27, 2023, in Boston, MA.

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