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Phase 1/2 Study of IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

Trial Profile

Phase 1/2 Study of IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 28 Jan 2025

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At a glance

  • Drugs IDP 023 (Primary) ; Isatuximab (Primary) ; Cyclophosphamide; Daratumumab; Fludarabine; Interleukin-2; Mesna; Rituximab
  • Indications Multiple myeloma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Acronyms Indapta-Trial1
  • Sponsors Indapta Therapeutics
  • Most Recent Events

    • 06 Dec 2024 According to an Indapta Therapeutics media release, company has amended its ongoing phase 1 study of IDP-023, to add a cohort of IDP-023 in combination with Sarclisa for patients with relapsed/refractory multiple myeloma.
    • 21 May 2024 According to an Indapta Therapeutics media release, the Cancer Prevention and Research Institute of Texas (CPRIT) has granted the company a competitive product development research award. The fund from $4.5 million grant will be used to treat additional patients in order to reach clinical proof-of-concept in our Phase 1 dose escalation trial Patient enrolled in phase I to date have received up to three planned doses of IDP-023 with or without interleukin-2.
    • 11 Jan 2024 According to an Indapta Therapeutics media release, company also announced that it has successfully manufactured sufficient IDP-023 to supply the Phase 1 clinical trial through the second half of 2024.

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