Trial Profile

A Phase Ib Dose Finding Study Assessing Safety and Activity of [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With Estrogen Receptor Positive, Human Epidermal Growth Factor Receptor-2 Negative and Gastrin Releasing Peptide Receptor Positive Advanced Breast Cancer Experiencing Early Relapse From (Neo)Adjuvant Endocrine Therapy or Who Have Progressed on Endocrine Therapy in Combination With a CDK4/6 Inhibitor for Advanced Disease

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 11 Jun 2026

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At a glance

Drugs Fulvestrant (Primary) ; Gallium 68 NeoBOMB1 (Primary) ; Goserelin (Primary) ; Lutetium-177 NeoBOMB1 (Primary) ; Ribociclib (Primary)
Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
Focus Adverse reactions
Sponsors Novartis Pharmaceuticals

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