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Auxora for the Treatment of AKI and Modulation of Injurious "Crosstalk" With the Lung: A Randomized Control Trial (KOURAGE)

Trial Profile

Auxora for the Treatment of AKI and Modulation of Injurious "Crosstalk" With the Lung: A Randomized Control Trial (KOURAGE)

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 06 Aug 2026

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At a glance

  • Drugs Zegocractin (Primary)
  • Indications Acute kidney injury
  • Focus Therapeutic Use
  • Acronyms KOURAGE

Most Recent Events

  • 29 Jul 2026 According to a CalciMedica media release, CalciMedica is evaluating the future development of Auxora in AKI, with no current plans to resume dosing in the KOURAGE trial.
  • 24 Jun 2026 According to a CalciMedica media release, the U.S. Food and Drug Administration (FDA) has reviewed a protocol amendment and interim safety data Following the applicable review period, the Company has received no comments from the FDA on the submission and the trial may continue to dose patients.
  • 06 May 2026 Planned End Date changed from 1 Apr 2026 to 1 Jul 2026.

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