A Phase I, Non-randomized, Open-label, Multi-center Dose Escalation Trial of Obrixtamig (BI 764532) Combined With Ezabenlimab in Patients With Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 10 Feb 2025

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At a glance

Drugs Obrixtamig (Primary) ; Ezabenlimab
Indications Large cell carcinoma; Neuroendocrine carcinoma; Small cell lung cancer
Focus Adverse reactions
Sponsors Boehringer Ingelheim

Most Recent Events

07 Feb 2025 Planned End Date changed from 6 Jun 2025 to 5 Sep 2025.
07 Feb 2025 Planned primary completion date changed from 6 Jun 2025 to 5 Sep 2025.
07 Oct 2024 Planned number of patients changed from 42 to 43.

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