An Open Label, Multicenter, Phase 1b/2a Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacokinetics of the ATR Inhibitor M1774 in Combination With Cemiplimab in Participants With Non-Squamous Non-Small Cell Lung Cancer That Has Progressed on Prior Anti-PD-(L)1 and Platinum-based Therapies (DDRiver NSCLC 322)
Latest Information Update: 24 Jul 2025
At a glance
- Drugs Cemiplimab (Primary) ; Tuvusertib (Primary)
- Indications Non-small cell lung cancer
- Focus Adverse reactions; Therapeutic Use
- Acronyms DDRiver NSCLC 322
Most Recent Events
- 14 Jul 2025 Planned End Date changed from 28 Feb 2026 to 30 Mar 2026.
- 14 Jul 2025 Planned primary completion date changed from 25 May 2025 to 30 Mar 2026.
- 27 Jan 2025 Planned End Date changed from 31 Mar 2025 to 28 Feb 2026.