DAREON™-5: An Open-label, Multi-center Phase II Dose Selection Trial of Intravenous BI 764532, a DLL3-targeting T Cell Engager, in Patients With Relapsed/Refractory Extensive-stage Small Cell Lung Cancer and in Patients With Other Relapsed/Refractory Neuroendocrine Carcinomas

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 04 Mar 2025

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At a glance

Drugs Obrixtamig (Primary)
Indications Large cell carcinoma; Lung cancer; Neuroendocrine tumours; Small cell lung cancer
Focus Adverse reactions; Therapeutic Use
Acronyms DAREON-5; DareonTM-5
Sponsors Boehringer Ingelheim

Most Recent Events

20 Dec 2024 Planned End Date changed from 3 Jul 2026 to 30 Jul 2027.
20 Dec 2024 Planned primary completion date changed from 25 Sep 2025 to 30 Oct 2026.
15 Oct 2024 Status changed from recruiting to active, no longer recruiting.

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