Trial Profile

Natriuretic-ureothelic Adaptation of Body Fluid Homeostasis During SGLT-2 Inhibition and/or Mineralocorticoid Receptor Modulation in Patients With Chronic Kidney Disease. A 4-arm, Double-blind, Double-dummy, Parallel-group, Phase 2 Study to Investigate the Mechanistic Effects of Dapagliflozin, Dapagliflozin + Balcinrenone, Balcinrenone and Placebo on Body Solute and Water Homeostasis and Energy Metabolism in Male and Female Participants Over 50 Years of Age With Chronic Kidney Disease.

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 13 May 2025

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At a glance

07 May 2025 Planned number of patients changed from 150 to 100.
07 May 2025 Planned End Date changed from 31 Jan 2025 to 30 Jun 2026.
07 May 2025 Planned primary completion date changed from 31 Jan 2025 to 31 Jan 2026.

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