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A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

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Trial Profile

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Apr 2025

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At a glance

  • Drugs Upadacitinib (Primary)
  • Indications Hidradenitis suppurativa
  • Focus Registrational; Therapeutic Use
  • Acronyms Step-Up HS
  • Sponsors AbbVie

    • Most Recent Events

    • 14 Feb 2025 Planned primary completion date changed from 1 Oct 2025 to 1 Feb 2026.
    • 25 Nov 2024 Planned primary completion date changed from 24 Nov 2025 to 1 Oct 2025.
    • 24 Jul 2023 According to AbbVie media release, the first patient has been dosed in this trial and aims to enroll approximately 1,300 participants across 275 sites worldwide.

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