Trial Profile

A Phase 1, Open-label, Drug-Drug Interaction Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple CYP450 Substrates in Patients With Moderate to Severe Atopic Dermatitis

Status: Completed

Phase of Trial: Phase 0

Latest Information Update: 22 Jan 2025

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At a glance

Drugs Metoprolol (Primary) ; Midazolam (Primary) ; Omeprazole (Primary) ; Rocatinlimab (Primary) ; Warfarin (Primary) ; Caffeine; Vitamin K
Indications Atopic dermatitis
Focus Pharmacokinetics
Sponsors Amgen

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