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An Open-Label, Phase 1 Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Pharmacodynamics in Response to a Single Subcutaneous Dose of Fazirsiran (TAK-999) in Subjects With or Without Hepatic Impairment

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Trial Profile

An Open-Label, Phase 1 Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Pharmacodynamics in Response to a Single Subcutaneous Dose of Fazirsiran (TAK-999) in Subjects With or Without Hepatic Impairment

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Apr 2025

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At a glance

  • Drugs Fazirsiran (Primary)
  • Indications Alpha 1-antitrypsin deficiency
  • Focus Pharmacokinetics
  • Sponsors Takeda

Most Recent Events

  • 09 Apr 2025 Planned End Date changed from 15 Apr 2025 to 15 Sep 2025.
  • 09 Apr 2025 Planned primary completion date changed from 15 Apr 2025 to 15 Sep 2025.
  • 04 Apr 2025 Status changed from recruiting to active, no longer recruiting.

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