Trial Profile

A Randomized Trial of Trastuzumab Deruxtecan and Biology-Driven Selection of Neoadjuvant Treatment for HER2-positive Breast Cancer: ARIADNE

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 06 Jan 2025

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At a glance

Drugs Trastuzumab-deruxtecan (Primary) ; Carboplatin; Cyclophosphamide; Docetaxel; Epirubicin; Letrozole; Paclitaxel; Pertuzumab; Ribociclib; Trastuzumab
Indications Breast cancer; HER2 positive breast cancer; Male breast cancer
Focus Biomarker; Therapeutic Use
Acronyms ARIADNE

Most Recent Events

06 Mar 2024 Planned End Date changed from 31 Dec 2031 to 30 Apr 2032.
06 Mar 2024 Planned primary completion date changed from 1 Jun 2026 to 30 Apr 2027.
09 Oct 2023 Planned initiation date changed from 1 Jun 2023 to 9 Oct 2023.

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