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A Randomised Open-Label Controlled Trial of Pleural Irrigation With Normal Saline Versus Intrapleural Tissue Plasminogen Activator and DNase (Fibrinolytic Therapy) in Pleural Infection.

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Trial Profile

A Randomised Open-Label Controlled Trial of Pleural Irrigation With Normal Saline Versus Intrapleural Tissue Plasminogen Activator and DNase (Fibrinolytic Therapy) in Pleural Infection.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 27 Feb 2026

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At a glance

  • Drugs Dornase alfa (Primary) ; Alteplase
  • Indications Pleural disorders
  • Focus Therapeutic Use
  • Acronyms PENTAD-FT

Most Recent Events

  • 24 Feb 2026 Status changed from recruiting to completed.
  • 03 Sep 2023 Status changed from not yet recruiting to recruiting.
  • 20 Jun 2023 New trial record

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