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A Phase 1/2a, Multicenter, Open-Label, First in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1311 in Subjects With Advanced/Metastatic Solid Tumors

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Trial Profile

A Phase 1/2a, Multicenter, Open-Label, First in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1311 in Subjects With Advanced/Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 29 Nov 2024

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At a glance

  • Drugs DB-1311 (Primary)
  • Indications Adenocarcinoma; Carcinoma; Malignant melanoma; Non-small cell lung cancer; Oesophageal cancer; Prostate cancer; Small cell lung cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Duality Biologics

    • Most Recent Events

    • 23 Nov 2024 Planned number of patients changed from 280 to 450.
    • 23 Nov 2024 Planned End Date changed from 1 Apr 2025 to 1 Sep 2026.
    • 23 Nov 2024 Planned primary completion date changed from 1 Apr 2025 to 1 Sep 2026.

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