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A Multicenter Open-label Phase 1 Trial to Evaluate Safety and Preliminary Efficacy of Endovascularly Applied Vascular Targeted Photodynamic Therapy (VTP) for Patients With Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma

Trial Profile

A Multicenter Open-label Phase 1 Trial to Evaluate Safety and Preliminary Efficacy of Endovascularly Applied Vascular Targeted Photodynamic Therapy (VTP) for Patients With Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 11 Jun 2025

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At a glance

  • Drugs Padeliporfin (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer; Pancreatic ductal carcinoma
  • Focus Adverse reactions
  • Sponsors ImPact Biotech; Steba Biotech

Most Recent Events

  • 05 Jun 2025 According to an ImPact Biotech Media Release, first patient has been dosed in this study at the UCI Irvine Medical Center. Dr. Nadine Abi-Jaoudeh is the Principal Investigator of this trial at UCI Irvine Medical Center. The trial is actively enrolling in UCI Irvine Medical Center and City of Hope Medical Center. Preliminary data from this study is expected in 2H 2025.
  • 27 Aug 2024 Status changed from not yet recruiting to recruiting.
  • 19 May 2024 Planned primary completion date changed from 30 Apr 2025 to 30 May 2026.

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