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A Phase 1b Study to Evaluate HMBD-001 With or Without Chemotherapy in Participants With Advanced Solid Tumors Harboring NRG1 Gene Fusions or Selected HER3 Mutations

Trial Profile

A Phase 1b Study to Evaluate HMBD-001 With or Without Chemotherapy in Participants With Advanced Solid Tumors Harboring NRG1 Gene Fusions or Selected HER3 Mutations

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 17 Mar 2025

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At a glance

  • Drugs Antineoplastics (Primary) ; Docetaxel (Primary) ; Gemcitabine (Primary) ; HMBD 001 (Primary) ; Paclitaxel (Primary)
  • Indications Adenocarcinoma; Non-small cell lung cancer; Pancreatic cancer; Pancreatic ductal carcinoma; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Hummingbird Bioscience
  • Most Recent Events

    • 12 Mar 2025 Status changed from recruiting to active, no longer recruiting.
    • 13 Oct 2023 Planned number of patients changed from 54 to 68.
    • 08 Aug 2023 Status changed from not yet recruiting to recruiting.

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