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A Phase IIIb, Multi-center, Non-randomized, Parallel-group, Open-label, Hybrid Type I Study Evaluating the Efficacy, Safety, Implementation Effectiveness, and Patient-reported Outcomes of Oral Dolutegravir/Lamivudine Once-daily as a First-line Regimen Followed by Participant-determined Optional Switch to Long-acting Intramuscular Cabotegravir Plus Rilpivirine Every Two Months for the Maintenance of Virologic Suppression in Antiretroviral Therapy Naive Adults Living With HIV-1

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Trial Profile

A Phase IIIb, Multi-center, Non-randomized, Parallel-group, Open-label, Hybrid Type I Study Evaluating the Efficacy, Safety, Implementation Effectiveness, and Patient-reported Outcomes of Oral Dolutegravir/Lamivudine Once-daily as a First-line Regimen Followed by Participant-determined Optional Switch to Long-acting Intramuscular Cabotegravir Plus Rilpivirine Every Two Months for the Maintenance of Virologic Suppression in Antiretroviral Therapy Naive Adults Living With HIV-1

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Sep 2025

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At a glance

Most Recent Events

  • 14 Jul 2025 According to ViiV Healthcare media release, data from the phase IIIb VOLITION study presented at IAS 2025.
  • 14 Jul 2025 Results presented in the ViiV Healthcare media release Media Release.
  • 08 Jul 2025 According to ViiV Healthcare media release, First data from the phase IIIb VOLITION study will be presented at at the International AIDS Society 2025 Conference (IAS 2025) in Kigali, Rwanda.

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