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A Phase 1/2, Safety Lead-in and Dose Expansion, Open-label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Activity of Ivosidenib in Combination With Nivolumab and Ipilimumab in Previously Treated Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

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A Phase 1/2, Safety Lead-in and Dose Expansion, Open-label, Multicenter Trial Investigating the Safety, Tolerability, and Preliminary Activity of Ivosidenib in Combination With Nivolumab and Ipilimumab in Previously Treated Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 19 Dec 2024

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At a glance

  • Drugs Ipilimumab (Primary) ; Ivosidenib (Primary) ; Nivolumab (Primary)
  • Indications Cholangiocarcinoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Servier

    • Most Recent Events

    • 17 Dec 2024 Status changed from active, no longer recruiting to completed.
    • 26 Aug 2024 Status changed from recruiting to active, no longer recruiting.
    • 04 Jun 2024 Trial design were presented at the 60th Annual Meeting of the American Society of Clinical Oncology.

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