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A Randomized, Double-Blind, Placebo-Controlled Study of ALTO-300 With an Open-Label Extension in Adults With Major Depressive Disorder

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Study of ALTO-300 With an Open-Label Extension in Adults With Major Depressive Disorder

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 18 Feb 2025

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At a glance

  • Drugs Agomelatine (Primary)
  • Indications Major depressive disorder
  • Focus Therapeutic Use
  • Sponsors Alto Neuroscience
  • Most Recent Events

    • 12 Feb 2025 According to an Alto Neuroscience Media Release, based on the results of the interim analysis, the Phase 2b trial will continue with an increase of approximately 50 biomarker positive patients in the final analysis sample. Topline results are expected in mid-2026.
    • 12 Feb 2025 Interim results presented in an Alto Neuroscience Media Release.
    • 11 Dec 2024 According to an Alto Neuroscience Inc media release, Company announced presentation of this trial at the 63rd annual meeting of the American College of Neuropsychopharmacology (ACNP), in Phoenix, Arizona, held December 8-11, 2024.

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