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A phase 3, multicentric, randomized study comparing physician choice Rx and triple metronomic as second-line therapy in head and neck cancer

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Trial Profile

A phase 3, multicentric, randomized study comparing physician choice Rx and triple metronomic as second-line therapy in head and neck cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 23 May 2025

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At a glance

  • Drugs Afatinib (Primary) ; Capecitabine (Primary) ; Cetuximab (Primary) ; Fluorouracil (Primary) ; Nivolumab (Primary) ; Pembrolizumab (Primary) ; Celecoxib; Erlotinib; Methotrexate; Taxanes
  • Indications Carcinoma; Head and neck cancer; Squamous cell cancer
  • Focus Therapeutic Use

Most Recent Events

  • 30 Apr 2025 Results evaluating physician choice of standard systemic therapy versus triple metronomic therapy in the second-line treatment of head and neck cancer published in the Cancer Letters.
  • 04 Jul 2023 New trial record
  • 06 Jun 2023 Results presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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