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Phase 2, Open-label, Single Cohort, Multicenter Trial for Sequential Treatment of High Dose Cabozantinib on/After Progression on Cabozantinib Monotherapy in Advanced Renal Cell Carcinoma (Seq-Cabo)

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Trial Profile

Phase 2, Open-label, Single Cohort, Multicenter Trial for Sequential Treatment of High Dose Cabozantinib on/After Progression on Cabozantinib Monotherapy in Advanced Renal Cell Carcinoma (Seq-Cabo)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Oct 2025

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At a glance

  • Drugs Cabozantinib (Primary) ; Nivolumab (Primary)
  • Indications Renal cell carcinoma
  • Focus Therapeutic Use
  • Acronyms Seq-Cabo

Most Recent Events

  • 10 Oct 2025 Planned End Date changed from 31 Dec 2027 to 31 Dec 2028.
  • 10 Oct 2025 Planned primary completion date changed from 1 Sep 2025 to 1 Sep 2026.
  • 10 Jan 2025 Planned number of patients changed from 36 to 18.

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