A prospective, single-center, observational real-world study: evaluating the efficacy of pembrolizumab combined with standard chemotherapy (cisplatin/carboplatin + paclitaxel) in the first-line treatment of locally recurring head and neck squamous cell carcinoma under different TP53 and PIK3CA states and safety
Latest Information Update: 08 Jul 2023
At a glance
- Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
- Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Squamous cell cancer
- Focus Therapeutic Use
- 07 Jul 2023 New trial record
- 06 Jun 2023 Results (n=20; From January 8, 2020 until September 20 2022) assessing the efficacy and safety of pembrolizumab monotherapy or in combination with standard chemotherapy in patients locally recurrent head and neck squamous cell carcinoma, presented at the 59th Annual Meeting of the American Society of Clinical Oncology.