Combination of Sintilimab Celecoxib and Regorafenib in Mismatch Repair (MMR) Proficient Refractory Advanced Colorectal Cancer Without Liver Metastasis a Single Arm Phase II SINCERE Study.
Latest Information Update: 13 Feb 2024
At a glance
- Drugs Celecoxib (Primary) ; Regorafenib (Primary) ; Sintilimab (Primary)
- Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
- Focus Therapeutic Use
- Acronyms SINCERE; SINCERE Study
Most Recent Events
- 04 Feb 2024 Planned number of patients changed from 33 to 44.
- 04 Feb 2024 Planned End Date changed from 20 Aug 2025 to 20 Dec 2025.
- 04 Feb 2024 Planned primary completion date changed from 20 Aug 2024 to 20 Sep 2025.