A Phase II, Open-label, Multicentre, Non-comparative, Single-arm Local Study of Ceralasertib Plus Durvalumab in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer Without Actionable Genomic Alterations, and Whose Disease Has Progressed On or After Prior Anti-PD-(L)1 Therapy and Platinum-based Chemotherapy
Latest Information Update: 29 Nov 2024
At a glance
- Drugs Ceralasertib (Primary) ; Durvalumab (Primary)
- Indications Non-small cell lung cancer
- Focus Therapeutic Use
- Acronyms LOTOS
- Sponsors AstraZeneca
Most Recent Events
- 17 May 2024 Planned End Date changed from 29 Jun 2025 to 29 Jul 2025.
- 17 May 2024 Planned primary completion date changed from 29 Jun 2024 to 29 Jul 2024.
- 07 Feb 2024 Status changed from recruiting to active, no longer recruiting.