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A Phase 2a Clinical Trial to Evaluate the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa

Trial Profile

A Phase 2a Clinical Trial to Evaluate the Safety and Immunogenicity of MTBVAC in Adolescents and Adults Living With and Without HIV in South Africa

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 25 Mar 2025

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At a glance

  • Drugs BCG (Primary) ; MTBVAC (Primary)
  • Indications Tuberculosis
  • Focus Adverse reactions; Pharmacodynamics
  • Acronyms HVTN605A5421

Most Recent Events

  • 24 Mar 2025 According to Bharat Biotech media release, The Phase2 HIV safety study is carried out by HIV Vaccine Trials Network (HVTN) and is funded by the Division of AIDS (DAIDS), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Department of Health and Human Services (DHHS).
  • 09 Aug 2024 Planned End Date changed from 30 Nov 2024 to 2 Feb 2026.
  • 09 Aug 2024 Planned primary completion date changed from 30 Nov 2024 to 2 Feb 2026.

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