Trial Profile

A Phase 1B Study of Combination ATR (M1774) and BET Inhibition (ZEN00-3694) to Exploit ARID1A Loss in Recurrent Ovarian and Endometrial Cancer

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 04 Oct 2025

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At a glance

Drugs Tuvusertib (Primary) ; ZEN 3694 (Primary)
Indications Adenocarcinoma; Endometrial cancer; Ovarian cancer
Focus Adverse reactions; Pharmacodynamics

Most Recent Events

15 Sep 2023 Planned initiation date changed from 12 Aug 2023 to 27 May 2024.
15 Sep 2023 Status changed from not yet recruiting to recruiting.
20 Jul 2023 New trial record

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