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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-0616 in Adults With Heterozygous Familial Hypercholesterolemia

Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-0616 in Adults With Heterozygous Familial Hypercholesterolemia

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 13 Nov 2025

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At a glance

  • Drugs Enlicitide decanoate (Primary)
  • Indications Hyperlipoproteinaemia type IIa
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms CORALreef HeFH
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 09 Nov 2025 According to Merck media release, Merck plans to share data from this trial, along with data from CORALreef Lipids and CORALreef AddOn with regulatory authorities worldwide.
  • 09 Nov 2025 According to Merck media release, the data from the trial were presented at the American Heart Association (AHA) Scientific Sessions 2025 and simultaneously published in the Journal of the American Medical Association.
  • 09 Nov 2025 Results presented in the Merck & Co Media Release.

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