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Tucatinib in Combination With Oral Etoposide (VP16) - Trastuzumab in Patients With Metastatic HER2+ Breast Cancer After Progression Under Tucatinib-Capecitabine-Trastuzumab or Toxicity Related to Capecitabine: a Multicenter Phase II

Trial Profile

Tucatinib in Combination With Oral Etoposide (VP16) - Trastuzumab in Patients With Metastatic HER2+ Breast Cancer After Progression Under Tucatinib-Capecitabine-Trastuzumab or Toxicity Related to Capecitabine: a Multicenter Phase II

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 31 Mar 2025

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At a glance

  • Drugs Etoposide (Primary) ; Trastuzumab (Primary) ; Tucatinib (Primary)
  • Indications Advanced breast cancer; HER2 positive breast cancer; Male breast cancer
  • Focus Therapeutic Use
  • Acronyms TUC-TOC

Most Recent Events

  • 27 Mar 2025 Planned End Date changed from 19 Dec 2027 to 19 Dec 2028.
  • 27 Mar 2025 Planned primary completion date changed from 19 Dec 2026 to 19 Dec 2027.
  • 25 Jan 2024 Planned End Date changed from 12 Dec 2027 to 19 Dec 2027.

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