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A Phase 1, Open-label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of VVD-130037, a Kelch-like ECH Associated Protein 1 (KEAP1) Activator, in Participants With Advanced Solid Tumors

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A Phase 1, Open-label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of VVD-130037, a Kelch-like ECH Associated Protein 1 (KEAP1) Activator, in Participants With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Mar 2025

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At a glance

  • Drugs BAY 3605349 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Vividion Therapeutics

    • Most Recent Events

    • 19 Mar 2025 Planned number of patients changed from 80 to 280.
    • 18 Sep 2023 According to Vividion Therapeutics media release, company has initiated dosing of patients in this trial.
    • 07 Aug 2023 Status changed from not yet recruiting to recruiting.

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