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Phase I/II Trial of Cord Blood-Derived NK Cells Genetically Engineered With NY-ESO-1 TCR/IL-15 Cell Receptor for Relapsed/Refractory Multiple Myeloma

Trial Profile

Phase I/II Trial of Cord Blood-Derived NK Cells Genetically Engineered With NY-ESO-1 TCR/IL-15 Cell Receptor for Relapsed/Refractory Multiple Myeloma

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Jun 2025

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At a glance

  • Drugs NY-ESO-1 TCR-T cell therapy (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Multiple myeloma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 30 Apr 2024 According to a Replay media release, this study anticipated to commence Q3 2024.
  • 30 Apr 2024 According to a Replay media release, the company announced the Food & Drug Administration (FDA) has approved the Investigational New Drug (IND) application for PRAME TCR/IL-15 NK,relapsed/refractory myeloid malignancies.
  • 11 Mar 2024 According to a Replay media release, company today announced that the first patient has been dosed in the Phase 1/2 study of NY-ESO-1 TCR/IL-15 NK.

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