A Phase 3, Open Label, Randomized Study to Compare the Efficacy and Safety of Odronextamab (REGN1979), an Anti-CD20 x Anti-CD3 Bispecific Antibody, in Combination With Lenalidomide Versus Rituximab in Combination With Lenalidomide Therapy in Relapsed/Refractory Participants With Follicular Lymphoma and Marginal Zone Lymphoma (OLYMPIA-5)
Latest Information Update: 25 Aug 2026
At a glance
- Drugs Odronextamab (Primary) ; Lenalidomide; Rituximab
- Indications Follicular lymphoma; Marginal zone B-cell lymphoma
- Focus Adverse reactions; Registrational; Therapeutic Use
- Acronyms Olympia-5
- Sponsors Regeneron Pharmaceuticals
Most Recent Events
- 14 Aug 2026 Planned number of patients changed from 470 to 580.
- 14 Aug 2026 Planned End Date changed from 23 Jan 2029 to 30 Apr 2031.
- 14 Aug 2026 Planned primary completion date changed from 23 Jan 2029 to 30 Apr 2031.