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A Phase 1, Open-label, Fixed-sequence Study to Investigate the Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Subjects

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Trial Profile

A Phase 1, Open-label, Fixed-sequence Study to Investigate the Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 15 Dec 2023

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At a glance

  • Drugs Brensocatib (Primary) ; Clarithromycin (Primary)
  • Indications Bronchiectasis; Chronic obstructive pulmonary disease; COVID 2019 infections; Cystic fibrosis; Hidradenitis suppurativa; Rhinosinusitis
  • Focus Pharmacokinetics
  • Sponsors Insmed

Most Recent Events

  • 08 Dec 2023 Status changed from recruiting to completed.
  • 11 Aug 2023 Status changed from not yet recruiting to recruiting.
  • 02 Aug 2023 New trial record

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