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Phase II Randomized Clinical Trial to Evaluate the Efficacy of the Addition of Polatuzumab Vedotin to Standard Chemotherapy R-DHAP (POLA-R-DHAP) as Induction Pre-transplantation Therapy in Patients With Diffuse Large B-Cell Lymphoma Refractory/Relapsed After First Line Treatment.

Trial Profile

Phase II Randomized Clinical Trial to Evaluate the Efficacy of the Addition of Polatuzumab Vedotin to Standard Chemotherapy R-DHAP (POLA-R-DHAP) as Induction Pre-transplantation Therapy in Patients With Diffuse Large B-Cell Lymphoma Refractory/Relapsed After First Line Treatment.

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 23 May 2024

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At a glance

  • Drugs Polatuzumab vedotin (Primary) ; Cisplatin; Cytarabine; Dexamethasone; Rituximab
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma
  • Focus Therapeutic Use
  • Acronyms FIL_POLARDHAP
  • Most Recent Events

    • 20 May 2024 Status changed from discontinued to withdrawn prior to enrolment.
    • 20 May 2024 According to ClinicalTrials.gov: US National Institutes of Health, this trial was withdrawn due to sponsors decision
    • 06 Dec 2023 Planned End Date changed from 1 Oct 2028 to 1 Jan 2029.

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