Trial Profile

Phase 2a Proof-of-Concept, Multicenter, Randomized, Open Label Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of a Single Dose of the Combination M5717-pyronaridine as Chemoprevention in Asymptomatic Adults and Adolescents With Plasmodium Falciparum Malaria Infection (CAPTURE-2)

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 05 Feb 2025

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At a glance

Drugs Atovaquone/proguanil (Primary) ; Cabamiquine (Primary) ; Pyronaridine (Primary)
Indications Falciparum malaria
Focus Proof of concept; Therapeutic Use
Acronyms CAPTURE-2
Sponsors Merck KGaA

31 Jan 2025 Status changed from recruiting to completed.
19 Dec 2024 Planned End Date changed from 30 Nov 2024 to 29 Dec 2024.
19 Dec 2024 Planned primary completion date changed from 30 Nov 2024 to 29 Dec 2024.

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