An Open-Label, Phase 2b, Global Multicenter Cohort Trial to Assess the Safety and Efficacy of Zipalertinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Exon 20 Insertion and Uncommon/Single or Compound Epidermal Growth Factor Receptor Mutations.
Latest Information Update: 09 Jun 2025
At a glance
- Drugs Zipalertinib (Primary)
- Indications Brain metastases; Non-small cell lung cancer
- Focus Registrational; Therapeutic Use
- Acronyms REZILIENT2
- Sponsors Taiho Oncology
Most Recent Events
- 03 Jun 2025 Planned number of patients changed from 160 to 220.
- 12 Mar 2025 Planned End Date changed from 20 Oct 2025 to 28 Aug 2026.
- 12 Mar 2025 Planned primary completion date changed from 30 Jun 2025 to 28 Feb 2026.