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Phase 1, First-in-Human Study to Assess the Safety, Tolerability and Anti-tumor Activity of CDR404 in HLA-A-02:01 Participants With MAGE-A4 Expressing Solid Tumors

Trial Profile

Phase 1, First-in-Human Study to Assess the Safety, Tolerability and Anti-tumor Activity of CDR404 in HLA-A-02:01 Participants With MAGE-A4 Expressing Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 02 May 2025

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At a glance

  • Drugs CDR 404 (Primary)
  • Indications Bladder cancer; Head and neck cancer; Non-small cell lung cancer; Oesophageal cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors CDR-Life

Most Recent Events

  • 25 Apr 2025 According to CDR-Life media release, dose escalation is ongoing and patient data from the early stages of the Phase 1 trial will be reported later this year.
  • 13 Sep 2024 According to CDR-Life media release, first patient has been dosed in this trial.
  • 29 May 2024 According to CDR-Life media release, company announced that an abstract accepted is for online presentation at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, occurring May 31 - June 4 in Chicago, Illinois.

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