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A Phase 1, Open-Label, Multi-Center, Dose Escalation and Expansion Study of KB707 in Subjects with Locally Advanced or Metastatic Solid Tumor Malignancies

Trial Profile

A Phase 1, Open-Label, Multi-Center, Dose Escalation and Expansion Study of KB707 in Subjects with Locally Advanced or Metastatic Solid Tumor Malignancies

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 27 May 2025

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At a glance

  • Drugs KB 707 (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Acronyms Opal 1
  • Sponsors Krystal Biotech

Most Recent Events

  • 30 Jan 2025 Planned number of patients changed from 140 to 240.
  • 30 Jan 2025 Planned End Date changed from 1 Jul 2026 to 1 Jul 2027.
  • 30 Jan 2025 Planned primary completion date changed from 1 Jul 2026 to 1 Jul 2027.

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