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A Two-part, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of APG777 in Patients With Moderate-to-severe Atopic Dermatitis

Trial Profile

A Two-part, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of APG777 in Patients With Moderate-to-severe Atopic Dermatitis

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 22 Sep 2026

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At a glance

  • Drugs Zumilokibart (Primary) ; Lebrikizumab
  • Indications Atopic dermatitis
  • Focus Proof of concept; Therapeutic Use
  • Acronyms APEX
  • Sponsors Apogee Therapeutics

Most Recent Events

  • 10 Aug 2026 Results presented in the Apogee Therapeutics media release.
  • 27 May 2026 Results of positive 16-week data from Part B induction dose optimization from this clinical trial presented in an Apogee Therapeutics media release.
  • 27 May 2026 According to an Apogee Therapeutics media release, company will hold a live webcast to discuss the Blackstone transaction and the results of the APEX Phase 2 Part B trial today at 8:00 a.m. ET.

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