Trial Profile

A Multicenter, Open-label, Phase 1 Dose Escalation and Expansion Study of TXN10128, an Inhibitor of ENPP1 as Monotherapy and Combination Therapy With Irinotecan or Paclitaxel in Locally Advanced or Metastatic Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 30 Apr 2025

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At a glance

24 Apr 2025 Protocol was amended to add combination arm with Irinotecan and paclitaxel, patient number increased.
24 Apr 2025 Planned number of patients changed from 36 to 96.
24 Apr 2025 Planned End Date changed from 30 Aug 2025 to 30 Jun 2026.

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