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A Phase 1, Open-Label, Two-Part, Fixed-Sequence, Drug-Drug Interaction Study to Evaluate the Effect of Voxelotor on the Pharmacokinetics of Selected CYP and Transporter Probe Substrates in Healthy Participants

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A Phase 1, Open-Label, Two-Part, Fixed-Sequence, Drug-Drug Interaction Study to Evaluate the Effect of Voxelotor on the Pharmacokinetics of Selected CYP and Transporter Probe Substrates in Healthy Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Nov 2024

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At a glance

  • Drugs Voxelotor (Primary) ; Bupropion; Flurbiprofen; Furosemide; Metformin; Midazolam; Omeprazole; Repaglinide; Rosuvastatin
  • Indications Sickle cell anaemia
  • Focus Pharmacokinetics
  • Sponsors Pfizer

    • Most Recent Events

    • 01 Nov 2023 Status changed from active, no longer recruiting to completed.
    • 11 Sep 2023 Status changed from recruiting to active, no longer recruiting.
    • 10 Aug 2023 New trial record

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