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A Randomized Phase 2 Study of Ompenaclid Versus Placebo in Combination With FOLFIRI Plus Bevacizumab in Patients With Previously Treated RAS Mutant Advanced or Metastatic Colorectal Cancer

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Trial Profile

A Randomized Phase 2 Study of Ompenaclid Versus Placebo in Combination With FOLFIRI Plus Bevacizumab in Patients With Previously Treated RAS Mutant Advanced or Metastatic Colorectal Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Mar 2025

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At a glance

  • Drugs Ompenaclid (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Irinotecan
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Sponsors Inspirna

Most Recent Events

  • 04 Mar 2025 Planned End Date changed from 31 Dec 2026 to 31 Mar 2025.
  • 04 Nov 2024 Planned End Date changed from 1 Aug 2028 to 31 Dec 2026.
  • 04 Nov 2024 Planned primary completion date changed from 1 Aug 2026 to 30 Sep 2025.

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