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A Phase 1a/1b Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of BBO-8520 in Subjects with Advanced KRASG12C Mutant Non-Small Cell Lung Cancer - the ONKORAS-101 Study

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Trial Profile

A Phase 1a/1b Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of BBO-8520 in Subjects with Advanced KRASG12C Mutant Non-Small Cell Lung Cancer - the ONKORAS-101 Study

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Mar 2025

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At a glance

  • Drugs BBO 8520 (Primary) ; Pembrolizumab (Primary)
  • Indications Colorectal cancer; Non-small cell lung cancer
  • Focus Adverse reactions; First in man
  • Acronyms ONKORAS-101

    • Most Recent Events

    • 16 Jan 2025 Planned number of patients changed from 229 to 250.
    • 14 Oct 2024 Planned number of patients changed from 160 to 229.
    • 06 Jun 2024 According to a BridgeBio Pharma media release, the first patient has been dosed in the ONKORAS-101 trial

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