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A Phase 1 Study to Evaluate the Safety and Preliminary Efficacy of ATA3219, Allogeneic Anti-CD19 Chimeric Antigen Receptor T-cell Therapy, in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

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Trial Profile

A Phase 1 Study to Evaluate the Safety and Preliminary Efficacy of ATA3219, Allogeneic Anti-CD19 Chimeric Antigen Receptor T-cell Therapy, in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Status: Suspended
Phase of Trial: Phase I

Latest Information Update: 10 Mar 2025

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At a glance

  • Drugs ATA 3219 (Primary)
  • Indications B-cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions
  • Sponsors Atara Biotherapeutics

    • Most Recent Events

    • 07 Mar 2025 According to Atara Biotherapeutics media release, First patient successfully completed dosing in the Phase I dose escalation study, evaluating the safety and efficacy of ATA3219
    • 21 Jan 2025 According to Atara Biotherapeutics media release, the company announced that the U.S. Food FDA has placed a clinical hold on company's Investigational New Drug (IND) application. Screening and enrollment of new participants have been paused and specifically identified subjects currently enrolled in the study who have the potential to derive clinical benefit may continue to receive treatment in accordance with the study protocol.
    • 21 Jan 2025 Status changed from recruiting to suspended since the starting materials used in ATA3219 production are affected by the compliance issues.

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