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A Modular Open Label, Signal Seeking, Phase II Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

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Trial Profile

A Modular Open Label, Signal Seeking, Phase II Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 26 May 2026

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At a glance

  • Drugs Alpelisib (Primary) ; Mirdametinib (Primary)
  • Indications Vascular malformations
  • Focus Therapeutic Use
  • Acronyms TARGET-VM

Most Recent Events

  • 05 May 2026 Planned End Date changed from 1 Dec 2026 to 1 May 2027.
  • 05 May 2026 Planned primary completion date changed from 1 Aug 2026 to 1 Jan 2027.
  • 24 Nov 2024 Status changed from not yet recruiting to recruiting.

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