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DAREON™-9: A Phase Ib Open-label Dose Escalation and Dose Confirmation Safety Study of Intravenous BI 764532 in Combination With a Single Agent Chemotherapy for the Treatment of Patients With Relapsed/Refractory Small Cell Lung Cancer After Platinum-based Chemotherapy

Trial Profile

DAREON™-9: A Phase Ib Open-label Dose Escalation and Dose Confirmation Safety Study of Intravenous BI 764532 in Combination With a Single Agent Chemotherapy for the Treatment of Patients With Relapsed/Refractory Small Cell Lung Cancer After Platinum-based Chemotherapy

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 02 May 2025

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At a glance

  • Drugs Obrixtamig (Primary) ; Topotecan (Primary) ; Topotecan (Primary)
  • Indications Small cell lung cancer
  • Focus Adverse reactions
  • Acronyms DAREON-9
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 24 Mar 2025 Planned number of patients changed from 65 to 90.
  • 24 Mar 2025 Planned End Date changed from 21 Nov 2026 to 30 Apr 2027.
  • 24 Mar 2025 Planned primary completion date changed from 21 Jan 2026 to 30 Jun 2026.

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