Trial Profile

MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer

Status: Recruiting

Phase of Trial: Phase II/III

Latest Information Update: 29 Jun 2025

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At a glance

Drugs Nivolumab (Primary) ; Relatlimab (Primary)
Indications Bladder cancer; Carcinoma; Pelvic cancer; Renal cancer; Ureteral neoplasms; Urethral cancer; Urogenital cancer
Focus Therapeutic Use
Acronyms MODERN

Most Recent Events

13 Jun 2025 Protocol amended with new indications urethra, ureter or renal pelvis cancer.
13 Jun 2025 Planned number of patients changed from 1190 to 992.
11 May 2025 Planned End Date changed from 11 Apr 2026 to 2 Sep 2030.

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