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MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer

Trial Profile

MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 04 Jun 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Relatlimab (Primary)
  • Indications Bladder cancer; Carcinoma; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms MODERN

Most Recent Events

  • 11 May 2025 Planned End Date changed from 11 Apr 2026 to 2 Sep 2030.
  • 11 May 2025 Planned primary completion date changed from 11 Apr 2026 to 2 Sep 2030.
  • 01 Apr 2024 According to a Natera media release, In the Alliance A032103 (MODERN) trial, approximately 1,000 patients will be enrolled at more than 300 sites in North America.

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