Trial Profile

A Phase I/II Study Evaluating M1774, an ATR Inhibitor, in Combination With Fulvestrant in Hormone Receptor-positive and HER2-negative, Advanced Breast Cancers, Resistant to CDK4/6 Inhibitor Plus Aromatase Inhibitor-based Endocrine Treatment

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 03 Apr 2024

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At a glance

Drugs Fulvestrant (Primary) ; Tuvusertib (Primary)
Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
Focus Adverse reactions
Acronyms MATRIX

27 Mar 2024 Planned End Date changed from 15 Sep 2027 to 15 Oct 2027.
27 Mar 2024 Planned primary completion date changed from 1 Mar 2027 to 1 Apr 2027.
27 Mar 2024 Planned initiation date changed from 1 Apr 2024 to 1 May 2024.

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